Example of a primary drying design space graph showing sublimation
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![Example of a primary drying design space graph showing sublimation](https://www.researchgate.net/publication/336956818/figure/fig1/AS:820455409733632@1572623221109/Typical-product-temperature-profile-in-a-lyophilization-vial-during-freezing.jpg)
Typical product temperature profile in a lyophilization vial during
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Recommended Best Practices for Lyophilization Validation—2021 Part
![Example of a primary drying design space graph showing sublimation](https://i1.rgstatic.net/ii/profile.image/333495818833921-1456523007572_Q512/Petr-Kazarin.jpg)
Petr KAZARIN, Postdoctoral Research Associate
![Example of a primary drying design space graph showing sublimation](https://www.tandfonline.com/cms/asset/ce41bae0-d700-48d1-8a27-64e27bc2ab85/ldrt_a_1791901_f0001_c.jpg)
Full article: Integrated use of mechanistic models and targeted experiments for development, scale-up and optimization of lyophilization cycles: A single vial approach for primary drying
![Example of a primary drying design space graph showing sublimation](https://www.mdpi.com/processes/processes-03-00406/article_deploy/html/images/processes-03-00406-g009.png)
Processes, Free Full-Text
![Example of a primary drying design space graph showing sublimation](https://media.springernature.com/m685/springer-static/image/art%3A10.1208%2Fs12249-021-02086-8/MediaObjects/12249_2021_2086_Fig1_HTML.png)
Recommended Best Practices for Lyophilization Validation—2021 Part
![Example of a primary drying design space graph showing sublimation](https://www.researchgate.net/publication/365901218/figure/fig1/AS:11431281104147689@1669954631398/Top-Comparison-between-freezing-profiles-for-the-old-cycle-red-and-new-cycle-blue_Q320.jpg)
Feroz Jameel's research works Gilead Sciences, Foster City and
![Example of a primary drying design space graph showing sublimation](https://www.researchgate.net/publication/336956818/figure/fig2/AS:820455409721344@1572623221144/Typical-primary-drying-design-space.png)
Typical primary drying design space
![Example of a primary drying design space graph showing sublimation](https://www.mdpi.com/processes/processes-10-02059/article_deploy/html/images/processes-10-02059-g013-550.jpg)
Processes, Free Full-Text
![Example of a primary drying design space graph showing sublimation](https://www.researchgate.net/publication/326445653/figure/fig2/AS:649362434695174@1531831477654/Measured-capacitance-vs-temperature-for-each-of-the-sensing-elements-where-Sensing_Q320.jpg)
Tong ZHU, Senior Scientist I, Ph.D. in Aero Eng.
![Example of a primary drying design space graph showing sublimation](https://ars.els-cdn.com/content/image/1-s2.0-S0378517322009723-gr12.jpg)
The graphical design space for the primary drying phase of freeze Drying: Factors affecting the dried product layer resistance - ScienceDirect
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PDF] Elements of Quality by Design in Development and Scale-Up of Freeze- Dried Parenterals
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Processes, Free Full-Text
Example of primary drying design space including choke flow limits for
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